Buy High Grade 51352-87-5 PRL-8-53 with Fast Delivery and Cheapest Price
- Molecular Formula:C18H22ClNO2
- Molecular Weight:319.83
- Vapor Pressure:1.43E-06mmHg at 25°C
- Boiling Point:398.9 °C at 760 mmHg
- Flash Point:134 °C
- PSA：29.54000
- LogP:3.94970
PRL-8-53(Cas 51352-87-5) Usage
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Description
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PRL-8-53, also known as methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate, is a synthetic nootropic compound developed by Dr. Nikolaus Hansl at Creighton University in the 1970s. It falls under the category of experimental nootropic research chemicals and has shown potential memory-enhancing effects, particularly in short-term memory. |
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Uses
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PRL-8-53 gained attention due to its hypermnesic properties, demonstrated in a human trial involving 47 healthy volunteers. In this double-blind trial, participants were given 5 mg of PRL-8-53 orally before cognitive tasks. Results showed significant improvements in memory recall, especially among older participants and those with initially poorer memory performance. However, individuals with higher baseline scores showed less improvement, possibly due to a ceiling effect. Despite its potential, PRL-8-53 is not recognized as a treatment for any specific disease or disorder. It has been suggested to have a nootropic effect in healthy individuals. No adverse effects were reported during the trial. |
InChI:InChI=1/C18H21NO2.ClH/c1-19(14-16-7-4-3-5-8-16)12-11-15-9-6-10-17(13-15)18(20)21-2;/h3-10,13H,11-12,14H2,1-2H3;1H
51352-87-5 Relevant articles
PRL-8-53: Enhanced learning and subsequent retention in humans as a result of low oral doses of new psychotropic agent
G Ramachandran
, Psychopharmacology, Volume 56, pages 249–253, (1978)
Using the serial anticipation method under double-blind conditions it was found that PRL-8-53 causes slight improvement of acquisition. Retention of verbal information was found improved to a statistically significant degree (most P values better than 0.01, some better than 0.001).
Learning and Memory Improvement through Chemistry: Dream or Reality in the Offing?
Hansl, Nikolaus R.; Hansl, Adele B.
, Phi Delta Kappan, v61 n4 p264-65 Dec 1979
Reports on PRL-8-53, an experimental drug that will boost the chemical system in the brain called the cholinergic system and thereby improve one's ability to retrieve information from a preexisting information pool. (Author/IRT)
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