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Tianeptine sodium salt

  • Product Name: Tianeptine sodium salt
  • CasNo: 30123-17-2
  • Purity:
  • Appearance: white to yellowish powder

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CasNo: 30123-17-2

Molecular Formula: C21H24ClN2NaO4S

Appearance: white to yellowish powder

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  • Molecular Formula:C21H24ClN2NaO4S
  • Molecular Weight:458.93
  • Appearance/Colour:white to yellowish powder 
  • Melting Point:180 °C 
  • Boiling Point:609.2 °C at 760 mmHg 
  • Flash Point:322.2 °C 
  • PSA:97.92000 
  • Density:1.38 g/cm3 
  • LogP:4.39460 

Tianeptine sodium salt(Cas 30123-17-2) Usage

Description

Tianeptine Sodium Salt is the sodium salt form of Tianeptine, an atypical antidepressant known for its unique mechanism of action as a μ-opioid receptor agonist. It also interacts with the glutamate system, which contributes to its antidepressant and neuroprotective effects.
Properties ppearance: White to pale yellow solid or powder.
Chemical Properties: Soluble in organic solvents (ethanol, DMSO, dimethyl formamide) and moderately soluble in PBS (pH 7.2).
Melting Point: Decomposes at about 180°C.
Mechanism of Action Tianeptine selectively facilitates serotonin uptake (5-HT) without significant affinity for various other receptors, including 5-HT and dopamine receptors.
Effects on Neurotransmission Increases phosphorylation of the AMPA receptor GluR1 subunit, influencing glutamatergic transmission and neuroplasticity.

Uses

Tianeptine sodium salt hydrate has been used primarily as an antidepressant. It has been utilized in research as a selective serotonin reuptake enhancer (SSRE) during serotonin transporter (SERT) assays.

Preparation Stock solutions are made by dissolving Tianeptine sodium salt in suitable organic solvents. The stock solution can then be diluted in aqueous buffers or saline for biological experiments.

InChI:InChI=1/C21H25ClN2O4S.Na/c1-24-18-9-6-5-8-16(18)21(23-13-7-3-2-4-10-20(25)26)17-12-11-15(22)14-19(17)29(24,27)28;/h5-6,8-9,11-12,14,21,23H,2-4,7,10,13H2,1H3,(H,25,26);/q;+1

 

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