Factory Supply Wholesale 196078-30-5 Pramlintide Competitive Price
- Molecular Formula:C171H267N51O53S2.x(C2H4O2).x(H2O)
- Molecular Weight:3949.39
- PSA：1768.24000
- LogP:-3.45320
Pramlintide(Cas 196078-30-5) Usage
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Description
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Pramlintide is an injectable amylin analogue drug primarily used to treat patients with diabetes whose blood sugar levels cannot be adequately controlled by insulin alone or in combination with oral medications. It belongs to a class of medications known as antihyperglycemics. |
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Developed by Amylin Pharmaceuticals, pramlintide is sold as an acetate salt and is approved for use in individuals aged 16 years and above with both type 1 and type 2 diabetes. By mimicking the actions of the naturally occurring hormone amylin, pramlintide complements insulin therapy by regulating the appearance of glucose into the bloodstream after meals. |
| Functions |
Pramlintide functions through three primary mechanisms of action:
Slowing gastric emptying: It slows down the movement of food through the stomach.
Suppressing post-meal glucagon secretion: It helps reduce the release of glucagon, which can contribute to elevated blood sugar levels.
Increasing satiety: Pramlintide can lead to a feeling of fullness, which may help control appetite and food intake.
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| Uses |
Clinical trials have shown that long-term adjunctive treatment with pramlintide alongside insulin therapy can effectively reduce HbA1c levels (a marker of long-term blood sugar control) and induce weight loss in individuals with type 2 diabetes. |
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