Mots-c is , while it's Molecular Formula is C101H152N28O22S2.

What is the CAS number for Mots-c?

The CAS number of Mots-c is 1627580-64-6.

Product classification

Featured Products

Mots-c

Product Name: Mots-c
CasNo: 1627580-64-6
Purity:
Appearance:

Mobile/Wechat/WhatsApp: +852 61915425

Email:niki@healthtide-api.com

Inquiry

CasNo： 1627580-64-6

Molecular Formula： C101H152N28O22S2

Buy High Grade Reliable Quality MOTS-C 1627580-64-6 Efficient Shipping

Molecular Formula:C101H152N28O22S2
Molecular Weight:2174.6

Mots-c(Cas 1627580-64-6) Usage

Description	MOTS-c (Mitochondrial ORF of the Twelve S proteins-c) is a 16-amino-acid peptide. MOTS-c emerges as a key player in mitochondrial regulation, impacting various metabolic functions and stress responses. Ongoing research may uncover further therapeutic applications and clinical implications.
Targeting Muscle and Metabolism	Acts on muscle tissue. Regulates metabolism through the folate-purine-AMPK pathway.
Mediator of Mitochondrial Regulation	Regulates insulin and metabolic homeostasis. Key role in metabolic functions.
Stress-Induced Expression	Significantly expressed in response to stress or exercise. Translocates to the nucleus during metabolic stress.
Nuclear Gene Expression	Directs the expression of nuclear genes during metabolic stress. Promotes cell balance and stress adaptation.

1627580-64-6 Relevant articles

The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?

Noriyuki Fuku, Helios Pareja-Galeano, Hirofumi Zempo, Rafael Alis, Yasumichi Arai, Alejandro Lucia, Nobuyoshi Hirose

, Aging cell, Volume14, Issue6 December 2015 Pages 921-923

These include humanin, and the recently discovered mitochondrial open reading frame of the 12S rRNA-c (MOTS-c). Although more research is needed, we suggest that the m.1382A>C polymorphism located in the MOTS-c encoding mtDNA, which is specific for the Northeast Asian population, may be among the putative biological mechanisms explaining the high longevity of Japanese people.

MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis

Joseph C. Reynolds, Rochelle W. Lai, Jonathan S. T. Woodhead, James H. Joly, Cameron J. Mitchell, David Cameron-Smith, Ryan Lu, Pinchas Cohen, Nicholas A. Graham, Bérénice A. Benayoun, Troy L. Merry & Changhan Lee

, Nature Communications volume 12, Article number: 470 (2021)

Here, we report that mitochondrial-encoded MOTS-c can significantly enhance physical performance in young (2 mo.), middle-age (12 mo.), and old (22 mo.) mice. MOTS-c can regulate (i) nuclear genes, including those related to metabolism and proteostasis, (ii) skeletal muscle metabolism, and (iii) myoblast adaptation to metabolic stress.

Home

About us123

Products123

Polypeptide

chemical materials

API

News123

Contact Us123