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Benzocaine

  • Product Name: Benzocaine
  • CasNo: 94-09-7
  • Purity:
  • Appearance: white odourless crystals

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CasNo: 94-09-7

Molecular Formula: C9H11NO2

Appearance: white odourless crystals

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1.What is the Benzocaine ?

Benzocaine is a white odourless needle-like crystal, slightly soluble in water and easily soluble in organic solvents. For example: ethanol, chloroform, ether, soluble in almond oil, olive oil.

ChEBI: Benzocaine is a benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina. It has a role as a topical anaesthetic, an antipruritic drug, an allergen and a sensitiser. It is a benzoate ester and a substituted aniline.

Benzocaine (ethyl p-aminobenzoate) is used topically by itself or in combination with menthol or phenol in nonprescription dosage forms such as gels, creams, ointments, lotions, aerosols, and lozenges to relieve pain or irritation caused by such conditions as sunburn, insect bites, toothache, teething, cold sores or canker sores in or around the mouth, and fever blisters. Benzocaine is a lipophilic local anesthetic agent with a short duration of action. Like most amino ester-type local anesthetics, it is easily hydrolyzed by plasma cholinesterase. Because of its low pKa, however, it is un-ionized under most physiological conditions and, therefore, can only bind to the lipid side of the local anesthetic receptor. It also can easily cross membranes into systemic circulation to cause systemic toxicities. Furthermore, being a PABA derivative, it has similar allergenic properties to procaine and is contraindicated with sulfonamide antibacterial agents.

2.What is the CAS number for Benzocaine ?

The CAS number of Benzocaine is 94-09-7.

3.What are another words for Benzocaine ?

Synonyms for Benzocaine 94-09-7:Benzocaine (USP);Benzoicacid, p-amino-, ethyl ester (8CI);(p-(Ethoxycarbonyl)phenylamine;4-(Ethoxycarbonyl)aniline;4-(Ethoxycarbonyl)phenylamine;4-Aminobenzoic acidethyl ester;4-Carbethoxyaniline;Aethoform;Amben ethyl ester;Anaesthan-syngala;Anaesthin;Anesthesine;Benzoak;Benzocaine;Diet Ayds;Ethoform;Ethyl 4-aminobenzoate;Ethyl aminobenzoate;Ethyl p-aminobenzenecarboxylate;Ethyl p-aminophenylcarboxylate;Gingicaine;Identhesin;Keloform;NSC 41531;NSC 4688;Norcain;Norcaine;Ora-jel;Orabase-B;Orthesin;Parathesin;Parathesine;Slim Mint Gum;Solu H;p-(Ethoxycarbonyl)aniline;p-Aminobenzoic acid ethyl ester;p-Carbethoxyaniline;p-Ethoxycarboxylicaniline;

4.What is Benzocaine (94-09-7) used for?

Benzocaine is used as an anesthetic (Local and topical) that in products such as burn and sunburn remedies, hemorrhoidal creams, suppositories, creams for treatment of poison ivy, oral and gingival products, sore-throat sprays/lozenges, astringents, appetite suppressants, callus and wart remedies, athlete's-foot remedies, toothache- and denture-irritation products.

InChI:InChI=1/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3/p+1

Relevant articles related to Benzocaine:

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, p. 13172 - 13181 (2014)

Hydrogenation of ethyl p-nitrobenzoate on carbon-supported palladium-triphenylphosphine catalyst

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